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Lumoral: Significant steps in antibacterial oral care research

Lumoral: Significant steps in antibacterial oral care research

The Finnish oral care innovation Lumoral is of great interest to the academic world, and several new Lumoral studies have been launched in recent months. Koite Health Ltd’s Clinical Project Manager Mikko Kylmänen shares his thoughts on the latest Lumoral clinical studies in this article.

In November 2023, we started a Lumoral study in Lund, Sweden, focusing on fixed orthodontic appliances. This Koite Health sponsor study is a randomized clinical trial involving 40 young subjects. The measurements of the study are performed by dentist and doctor of odontology Ann-Marie Roos Jansåker, specialized in periodontology, in collaboration with specialist dentist Katja Elses. The clinical measurements will be made blinded, so that the investigator does not know whether a participant is using Lumoral or not. 

In January-February 2024, three new academic randomized Lumoral studies will start:

HEALTHIER: The study evaluates the effectiveness of Lumoral in the treatment of peri-implantitis. The study is conducted at a private clinic, Södertandläkarna, in Stockholm, Sweden, and a total of 80 subjects will participate.

LumOsteo: The study investigates the effect of Lumoral on the prevention of complications related to implant installation. The study is conducted at Hammaslääkärit Eteläranta 10 dental clinic in Helsinki, Finland, and a total of 40 subjects will participate.

Tartu University Dental Student Crossover Plaque Study: The study compares two different oral hygiene practices and their impact on oral health. The study is conducted in Tartu, Estonia, and has two test groups. Half of the participants will use Lumoral at the beginning, and after a break of two weeks, the groups switch: one half uses Lumoral, the other does not. This provides comparison results at both group and individual level. The study participants are healthy young adults.

On the innovation front, Lumoral studies have received approval for one thousand recruitable subjects, which indicates that researchers in the field are interested in this new approach to oral care. In 2024, the majority of Lumoral studies will be conducted by academic research groups, which is most encouraging.

- Studies with the Lumoral method open up new possibilities for the development of oral care. Our company is proud to promote health and well-being through innovative solutions. We continue to work closely with the research community and look forward to potential applications of Lumoral in the future," says Mikko Kylmänen, Research Manager at Koite Health Oy.

- It is great to see how much interest researchers are showing in Lumoral studies. In 2024, a large part of the Lumoral studies will be conducted by academic research groups, he continues.

For more information on the Lumoral studies and their effects, visit www.lumoralpro.com.



Fresh breath is the key to overall well-being

Fresh breath is the key to overall well-being

Valentine's Day is approaching – a celebration symbolizing love and friendship. Therefore, it is an appropriate moment to consider the importance of fresh breath in relationships. Good oral hygiene is not limited to just a smile; it can have a significant impact on interpersonal interactions, even in the workplace.

Everyone suffers from occasional bad breath, or halitosis. There can be several reasons for this condition. Understanding the root cause is important for addressing and preventing the problem. (1,2)

Halitosis is primarily caused by specific bacteria in the mouth, such as streptococci, which are also found in various infections in the body. Oral bacteria, especially those related to gum disease and periodontitis, can produce volatile sulfur compounds (VSCs) that cause foul odors in the mouth and may also be a sign of gum inflammation. These compounds are formed when oral bacteria break down food residues, especially proteins, and other organic substances. (3)

Certain foods, such as garlic, onions, and spices, can also cause bad breath. Avoiding these foods can be a simple way to keep your breath fresh. However, persistent bad breath may be a sign of underlying health issues. For example, diabetes is known to cause a specific acidic odor in the breath. So, if bad breath persists despite efforts to address the problem, it is important to consult a doctor. (4)

Fresh breath boosts confidence

Several studies indicate that bad breath can be a bigger problem for well-being than is commonly understood. Bad breath can cause social awkwardness and affect personal relationships because people may hesitate to engage in close conversations. Improving oral hygiene and regular dental check-ups can help manage and alleviate the social impact of bad breath. (5, 6)

Fresh breath is not only important in special situations, such as Valentine's Day, but also in everyday encounters in all social environments. Good oral hygiene and fresh breath promote the creation of a positive first impression and also influence professional advancement.

Valentine's Day is just around the corner. Read dentist Pirta Liljekvist's tips for achieving fresh breath:

Regular oral hygiene:

Brush your teeth at least twice a day and clean between your teeth once a day to remove food debris and plaque that can cause bad breath.

– Bad breath can signal to others that personal hygiene may be lacking. A polished appearance won't save the situation if your breath is stale, says dentist Pirta Liljekvist.

– It can be difficult to notice if your own breath smells. The floss test tells mercilessly how others perceive your breath, Liljekvist continues.

Stay hydrated:

Drink plenty of water throughout the day to keep your mouth moist and wash away bacteria. Dry mouth can lead to bad breath.

Fact: Without saliva, tooth decay and gum disease are more likely. If you have dry mouth, you need to be especially careful to follow good oral hygiene practices to combat tooth decay and gum disease.

Healthy diet:

Some foods temporarily cause bad breath. For example, otherwise healthy onions and garlic can still linger in your breath the next day. If you want your breath to smell fresh, avoid them. Fruits and vegetables make good snacks, just remember to always take breaks between meals. Snacking and too-short breaks between meals are harmful to your teeth.

Use sugar-free and xylitol products:

Tip: Chewing gum stimulates saliva production, which helps neutralize odors and keep breath fresh.

Quit smoking:

Smoking not only causes bad breath but also increases the risk of gum disease. Quitting smoking can improve overall oral health.

Limit alcohol consumption:

Alcohol can lead to dry mouth, which causes bad breath. Limit alcohol consumption to maintain saliva production. Many mouthwashes also contain alcohol. It's advisable to choose an alcohol-free mouthwash if that's what you prefer to use.

Regular dental visits:

Tip: Schedule regular dental check-ups to detect potential dental problems early.

– Finding the root cause of halitosis starts at the dentist's office. However, one's daily activities in everyday life are crucial. It's not worth letting bad breath become a social problem because there are ways to address it, Liljekvist suggests.

Lumoral freshens breath

Lumoral is an antibacterial and light-activated oral care method developed by Finnish researchers and designed to be used in addition to regular tooth brushing. The device is suitable for everyone but is especially useful for individuals facing oral health challenges. Lumoral treatment also freshens breath. Lumoral's antimicrobial effect targets bacteria in the mouth that cause inflammation but does not affect other oral mucosal bacteria. (7)

Lumoral slows down plaque formation and significantly reduces the number of bacteria that cause periodontitis. Although bad breath can be caused by many factors, improving oral hygiene is a good first step. Acquiring a high-quality electric toothbrush is an easy way to improve oral health. Adding Lumoral treatment to your daily oral hygiene routine enhances the effectiveness of oral cleaning and also helps when traditional oral hygiene methods are insufficient. (7)

Using mouthwashes is a common way to try to control bad breath, but the problem with antibacterial mouthwashes is that they destroy not only harmful bacteria but also the microbiota that promote oral health. Many mouthwashes also contain alcohol, which has been linked to the development of oral cancer in scientific studies (8). It is also important to note that long-term use of antibacterial mouthwashes, such as chlorhexidine, can adversely affect taste and cause tooth discoloration.

Lumoral treatment differs from mouthwashes in that it does not contain alcohol and targets plaque.

Lumoral's antibacterial effect has been shown to be stronger than mouthwashes, but because it is targeted, it does not disturb the diversity of the oral microbiome. Since bacteria cannot develop resistance to Lumoral treatment, it is suitable for regular use.

– Lumoral helps keep harmful mouth bacteria in check. As a dentist, I have noticed with pleasure at my practice that those who use Lumoral regularly have less gum inflammation than those who do not, emphasizes Pirta Liljeqvist.


Sources: 

  1.   Krespi YP, Shrime MG, Kacker A. The relationship between oral malodor and volatile sulfur compound-producing bacteria. Otolaryngol Head Neck Surg. 2006 Nov;135(5):671-6. doi: 10.1016/j.otohns.2005.09.036. PMID: 17071291.
  2.   Newman T. Everything you need to know about bad breath.https://www.medicalnewstoday.com/articles/166636
  3.   Medical Journal Duodecim, 26.1.2022, Osmo Saarelma, Specialist in General Medicine, Bad breath (halitosis)
  4.   González-Moles MÁ, Ramos-García P. State of Evidence on Oral Health Problems in Diabetic Patients: A Critical Review of the Literature. J Clin Med. 2021 Nov 18;10(22):5383. doi: 10.3390/jcm10225383. PMID: 34830663; PMCID: PMC8618619.
  5.   Veeresha KL, Bansal M, Bansal V. Halitosis: A frequently ignored social condition. J Int Soc Prev Community Dent. 2011 Jan;1(1):9-13. doi: 10.4103/2231-0762.86374. PMID: 24478947; PMCID: PMC3894075.
  6.   Wu, J., Cannon, R.D., Ji, P., Farella, M., Mei, L. (2020) Halitosis: prevalence, risk factors, sources, measurement and treatment – a review of the literature. Australian Dental Journal https://doi.org/10.1111/adj.12725
  7.   Pakarinen, S.; Saarela, R.K.T.; Välimaa, H.; Heikkinen, A.M.; Kankuri, E.; Noponen, M.; Alapulli, H.; Tervahartiala, T.; Räisänen, I.T.; Sorsa, T.; Pätilä, T. Home-Applied Dual-Light Photodynamic Therapy in the Treatment of Stable Chronic Periodontitis (HOPE-CP)-Three-Month Interim Results. Dent. J. 2022, 10, 206. https://doi.org/10.3390/dj10110206
  8.   Boffetta P, Hayes RB, Sartori S, et al. Mouthwash use and cancer of the head and neck: a pooled analysis from the International Head and Neck Cancer Epidemiology Consortium. Eur J Cancer Prev 2015; [Epub ahead of print] PubMed PMID: 26275006; PubMed Central PMCID: PMC4752930.

 

Dental disease that many overlook – this is what you should check for

Dental disease that many overlook – this is what you should check for

An untreated inflammation in the gums can eventually lead to periodontitis. Yet, many people overlook the symptoms of gingivitis, as it is also called. Here are the signs you should be on the lookout for - and the best tips for healthy gums.

Plaque, the bacterial buildup on teeth, causes 95 percent of all oral diseases. Gingivitis is no exception.

- Gingivitis is an inflammation that affects the dental tissue, i.e., the gums. It occurs because the harmful bacteria that we all have in our mouths have not been sufficiently removed, allowing them to grow, says Ing-Marie Albinsson, a dental hygienist at the Lilla Tandkronan clinic in Arvika.

The immune system responds to the bacteria by sending more white blood cells to the area. Blood flow increases, causing the gums to swell.

- Unfortunately, in this case, it has a somewhat undesired effect. The bacteria that caused the inflammation thrive especially well in an oxygen-poor environment, and protected by the swollen gums, they can grow even more, says Ing-Marie Albinsson.

The first sign of gingivitis is thus swollen gums, something that is not always easy to detect. The next step is that the gums become even more inflamed and start bleeding. At first, it occurs infrequently, but gradually more often and due to lighter strains.

- If it bleeds every time you brush your teeth or, for example, bite into an apple, then the inflammation has progressed relatively far, says Ing-Marie Albinsson.

Choose the right tool

The most important step to combat gingivitis is cleaning - both on and between the teeth.

- With the toothbrush, you only reach the free surfaces, such as the outside, inside, and chewing surfaces. But between the teeth, we need to use other tools, such as interdental brushes or dental floss, says Albinsson.

The choice of tool depends on the size of the gaps between the teeth. And how to use it is just as crucial.

- A large part of our treatment for patients with advanced gingivitis is education by the dental hygienist. If you don't use the right tool correctly, the effect is lacking, says Albinsson.

Dual Light treatment is effective

Succeeding in the treatment of gingivitis is incredibly important - because if it is not done, the consequences can be serious.

- If the bacteria continue to grow, they begin to grow downward, which can create deep pockets. Through them, the bacteria can eventually also reach the threads holding the teeth and attack them. This leads to periodontitis, says Albinsson.

To avoid this, Ing-Marie recommends a complementary treatment with the Finnish innovation Lumoral, which removes 99.9 percent of the harmful bacteria in our mouths through a patented light treatment. 

- When we brush our teeth, 65 percent of the bacteria disappear. With Lumoral, you get a completely different result. The method is easy to use and is especially effective for those who already have problems. But it can also be used preventively, both to stay healthy and to reduce the costs of future dental care, says Albinsson.

This is Lumoral

The Lumoral method removes microscopic plaque from the surface of teeth and gums, slows down the formation of new plaque, and delays the onset of tartar. Its effect is based on the light-activated Lumorinse mouthrinse. The treatment targets its antibacterial effect only on plaque and thus benefits the normal bacterial flora in the mouth. Lumoral is a CE-marked medical device.

Lumoral consists of a mint-flavored mouthrinse, Lumorinse, used in combination with the special mouthpiece. The treatment eliminates the ability of plaque to stick to the surfaces of teeth so that teeth become clean and teeth surfaces  smooth.

The at-home treatment takes 10 minutes and is recommended once or twice a week.

Lumoral Junior

For children, there is Lumoral Junior. The Lumoral Junior mouthpiece is suitable for children between 4 and 12 years old. From the age of 12, the Lumoral mouthpiece for adults is generally suitable for a child to use. To use Lumoral, the child should be able to rinse his or her mouth with a mouthrinse.