Obtaining dental care is more difficult during the current pandemic and this is causing an increase in dental problems such as dental cavity formation and gum disease. Researchers have introduced a home-use method for the reduction and prevention of dental disease.
Koite Health researchers have studied the efficacy and sustainability of the antibacterial effect of daily administered dual light on Streptococcus mutans biofilm. This was compared to single-wavelength antibacterial photodynamic therapy (aPDT) and antibacterial Blue light (aBL) treatments respectively.
The results indicate that when administered repeatedly to S. mutans biofilm, a single wavelength-based aBL or aPDT lead to a significant biofilm adaptation and increased S. mutans viability. The dual light, i. e. combined use of aBL light in synchrony with aPDT, arrests the adaptation and provides significantly improved and sustained antibacterial efficacy.
The results in the submitted article can be found in PLOS ONE journal.
Photodynamic therapy (PDT) was discovered by accident in 1900 by a medical student, Oscar Raab, in Munich. He was studying common freshwater bugs, paramecium, and noted that the organic compound acridine orange somehow sensitized the cells to light.
Historically, the use of PDT has been constrained by the invention of antibiotics. Recently, when antibiotic therapy has been compromised by the increasing development of antimicrobial resistance, interest in PDT has been renewed.
In dentistry, interest in antibacterial PDT has arisen because it has a clear effect on bacterial biofilms, unlike any other method. Not only does this method penetrate the biofilm matrix, but it also lacks resistance formation. However, the lack of availability of proper light sources has been holding back the implementation of the method on a grand scale. Therefore, in dentistry, PDT has thus far only been applied as an in-office treatment with laser systems against difficult-to-treat bacterial conditions. Through utilizing the advances of modern LED technology, Koite Health is now offering photodynamic light as part of one’s daily oral hygiene routine.
PDT research has been significantly increased over the last 15 years. This has been especially evident in dentistry, where multiple clinical studies have been conducted, mostly to find treatments for periodontal diseases. These studies, have shown that to achieve a profound effect, weekly continuous use is recommended. In all
The Lumoral® method is highly localized against dental plaque and it uses targeted light to offer the safest and most effective PDT technology for daily hygiene use and prevention of oral disease.