Finnish health technology company Koite Health Oy has signed a distribution agreement with a Danish distributor of specialized dentistry products in the tissue regenerative and surgical fields, such as dental implantology. Following the accord, Puredent ApS will also offer Lumoral® – the latest technology for improved oral health self-care – to consumers and oral health professionals in the Danish and Icelandic markets.

– Common to the solutions that we offer is that they can differentiate clinics from other clinics and help their patients reach better oral health, says Thomas Boas, Founder and CEO of Puremedical Group ApS.

Puredent is part of the Danish Puremedical Group – a company that operates in the dentistry, medical and veterinary fields. Thus far, the company's dentistry business has offered solutions mainly for the dental repair and restoration segments. Following the Lumoral agreement, Puredent will focus more marketing efforts on the continuously growing preventative oral care market in Denmark and Iceland. 

According to Boas, Lumoral is a unique product that helps prevent and treat common oral diseases such as gingivitis, periodontitis, and dental caries. 

Dental caries is the most common infectious disease in the world. According to the World Health Organisation (WHO), severe periodontal diseases are estimated to affect around 19% of the global adult population, representing over 1 billion cases worldwide. The main risk factors for periodontal disease are poor oral hygiene and tobacco use.

Boas notes that Lumoral fits well in the company's product line as more and more dentists and medical physicians are beginning to understand the close link between oral and general health. This also means that a growing number of dentists are starting to put increased emphasis on oral disease prevention.

Boas stresses that the current dental market situation differs from the pre-Covid-19 era five years ago. This is when Puredent first sought to enter the preventive oral health market with an innovative diagnostics test that reveals whether a person has periodontal disease or not in their mouth. The so-called Matrix metalloproteinase-8 immunological test (aMMP-8) developed by Dr. Timo Sorsa – Professor of Periodontology at Helsinki University and Karolinska University – helps detect whether there is a periodontal degradation process taking place in a person's gum pocket before it is even possible to see visually.

Professor Sorsa is one of the most respected periodontal researchers in the world. He has been developing and patenting many solutions for treating periodontitis, including the most validated clinical test for active periodontitis identification. 

– The market in Denmark was not ready then, but it is ready now. Increased knowledge of the link between oral diseases and general health encourages oral health professionals to provide early diagnosis and preventive care. This is where both the antibacterial Lumoral method and the aMMP-8 diagnostics test come in handy,  Boas notes.

According to Boas, even the Danish Association of Dentists is pushing the "Healthy Mouth, Healthy Body" theme today.

– Lumoral is a novel product category in preventative oral care. Minimal effort can have a significant effect. If you look at this from the dentists' point of view, Lumoral is a way to improve their patient's overall health as home care between the dental appointments.

According to Boas, the signed distribution deal helps to bridge Puremedical Group's dentistry and medical businesses closer together and create synergy benefits. 

Thomas Boas, Founder and CEO of Puremedical Group ApS.

Lumoral – a novel, cutting-edge technology 

The agreement between Koite Health and Puredent includes all activities necessary to launch a novel medical device and a new technology in the Danish and Icelandic markets. According to Boas, the agreement will initially mean focusing on B2C operations, making the Lumoral method available to the Danish consumer and Icelandic users through a local partner of Puredent.

Through extensive communication, the company seeks to ensure that dental professionals in the Danish B2B market are also introduced early to the benefits of Lumoral treatment so that they can start recommending the treatment to their patients.

Boas points out that good oral hygiene requires adequate motor and mental skills. For example, flossing or brushing can be difficult because of age or physical disability, leaving bacteria-filled dental plaque between teeth. On the other hand, even when brushing teeth perfectly, studies show that an effective electric toothbrush only removes about 65% of harmful oral bacteria.

– With Lumoral you can't go wrong. This is why the Lumoral method is so unique. With brushing and flossing, you must follow strict procedures (twice a day, 7 days a week, 2 minutes tooth brushing) to remove plaque efficiently from your mouth and reach optimal oral health. Still, the efforts might not be enough. With Lumoral you just swish the mouthwash in your mouth and then let the antibacterial effect of the mouthpiece do its work.

Boas says that it is crucial that scientific evidence of Lumoral's efficacy is communicated directly to dental professionals to help spread the message of Lumoral's scientifically proven effect on oral health. Several scientific studies that clearly show the clinical impact of Lumoral's antibacterial dual light therapy have already been released.

Lumoral is changing the future of dental care at home

Research shows that Lumoral's antibacterial aPDT phototherapy effectively eliminates harmful bacteria in the mouth while treating advanced gum disease. Similar light-activated antibacterial treatments have been used in dental clinics, for example. However, the problem has been the cost and frequency of these treatments to provide sufficient efficacy. 

Preventive health care, which includes the use of the antibacterial Lumoral method to improve oral hygiene, will quickly pay for itself. Preventive oral health care also brings significant savings to society. This applies not only to dental care but to the entire healthcare system. Lumoral supports regular mechanical dental hygiene, helps achieve gum health, and prevents inflammation when regular dental hygiene is insufficient.

Puredent aims at providing its customers with the best possible modern treatment for oral diseases.  

Boas sees multiple groups of people who can benefit most from using Lumoral. These include patients undergoing orthodontic treatment, patients into fitness sports and promoting healthy living habits, elderly patients with limited motor abilities, and competitive athletes as well as patient groups in cancer, diabetes and rheumatoid arthritis.

– The timing of this cooperation is likely to be very good. This cooperation is an exciting tool for expanding into the prevention business.

Sakari Nikinmaa, Koite Health's CEO, the partnership agreement's benefits are mutual. Partnership with Thomas Boas and his Puredent team are an important step for Lumoral to strengthen its reach in the Scandinavian market.

– Our strategy is to partner with industry leaders to raise awareness among professionals about the Lumoral product and its benefits and to build a global sales structure to secure product availability globally.

– By working together, we can take oral health to a new level and provide patients with the best possible treatment experience and outcomes. Koite Health's clinical results and Puredent's expertise and organization are perfectly combined with Lumoral's unique features and efficiency, says Nikinmaa.

Sakari Nikinmaa, Co-founder and CEO of Koite Health Oy.

Finland is a rather conservative country when it comes to dental implant treatments. Unlike in many other European countries, where demand for implants is growing strongly as the population ages, the growth in Finland has remained relatively moderate over the past 10-15 years. However, the need for implants is no less in our country.

According to specialist dentist Pekka Kallio, around 30 000 new dental implants are placed in Finland every year. In relation to the population, the number of implants in Italy, for example, is four times higher than in Finland. Meanwhile, around 100 million implants have been placed in patients' mouths worldwide so far. Around 10 million new dental implant treatments are done every year.

According to Kallio, the high cost of implant treatment in Finland compared to many other countries is often a barrier to more significant growth in the implantology business.

- However, with implant surgery becoming increasingly digitally guided, it is possible that patients in Finland will not have to pay so much for their implant treatments in the future. Price competition in the sector has already increased in Finland, without compromising the quality of treatment, says Kallio. 

Kallio has been a specialist dentist himself for almost 25 years. He recalls that dental implants come in handy when, for example, a patient needs a strong foundation for crowns or bridges.

According to Kallio, the success of implant treatments depends on both the experience of the dentist and the choice of the patient. All the implant brands used in Finland are of high quality, so the success of implant treatment is not dependent on the implant itself. A patient's previous history of periodontitis is also not an obstacle to implant treatment.

- However, periodontal disease must be treated and well maintained before implant treatment. The most important risk factor for treatment failure is smoking. Diabetes is another important risk factor to consider in treatment, says Kallio.

A healthy mouth is the basis for successful implant treatment

Oral home care, including thorough daily brushing and flossing and regular dentist check-ups are essential for the prognosis of the treatment. There is room for improvement in the oral home care of implant patients. The idea that implants are eternal and better than one's own teeth is wrong, says Kallio.

Peri-implantitis is a serious gum disease that affects the well-being of implants and can lead to implant loss if left untreated. Although implant treatments generally have a good success rate, on average one implant is lost every four minutes. This translates into around 140,000 lost implants per year. Around 50% of implant patients develop peri-implantitis over time, according to figures from Dentognostics.

Kallio points out that successful implant treatment requires a healthy mouth.

- Periodontal disease and implant treatments are not at all compatible. The risk of infection is high and, in the long run, teeth weakened by periodontal disease will cause excessive pressure to dental implants and bridges.  

After implant surgery, the surgical site is tender. In addition, sutures make cleaning difficult. Today, antiseptic mouthwashes are used to kill oral bacteria after surgery. However, they have side effects, including discolouration of the teeth, says Kallio. 

Antibacterial Lumoral treatment has also shown good results in the treatment of dental implant-related infections.

- In my studies, the amount of plaque and gum bleeding in patients was significantly reduced compared to the initial situation, and there were no side effects associated with the use of Lumoral, says Hanna Lähteenmäki, a YAMK oral hygienist who was awarded the title of Oral Hygienist of the Year 2022.

Kallio also feels that Lumoral is a promising product for implant patients.

- I use it selectively with my patients who have challenges with oral home care or other factors that affect the prognosis of their treatment.

- I recommend using Lumoral daily for 2 weeks before surgery and 2 weeks after surgery.  Most patients continue to use it at the normal 2 times a week dosage.

Even with successful implant placement, implants do not always remain healthy. According to Kallio long term follow-up studies have show inflammation and bone loss around implants, known as peri-implantitis. It occurs in about one fifth of implants after a ten-year follow-up.  Treatment of these often requires complex treatment by a specialist dentist. 

- Here too, careful oral home care is a prerequisite for successful treatment.  Lumoral is, in my opinion, an affordable insurance not only to improve the long-term prognosis of implant treatment, but also to prevent many other oral health risks, such as caries and periodontitis. For patients with dry mouth problems, Lumoral provides a definite improvement. The ease of use of Lumoral and the immediate feeling of dental cleanliness it provides has brought many positive comments from my patients.

Finnish health tech group Koite Health – named one of Europe’s hottest startup companies in 2022 – is proud to join the Expodental Meeting event in Rimini, Italy, on 18— 20 May 2023. Together Koite Health and Megagen Italia will present the Lumoral-method to the Italian market. Lumoral is an innovative technology designed to enhance oral home care for the prevention and treatment of gum diseases and dental caries.

Koite Health recently signed a distribution accord with Megagen Italia – a company, which markets cutting-edge dental implant systems and advanced surgical devices. As a kickoff to the new collaboration, both companies will be present at the Expodental Meeting.

The global dental implants market is flourishing because of a growing prevalence of dental diseases and tooth loss, an aging population, and the rapid adoption of technology advancements and digital technologies, such as computer-aided design and 3D printing, in dental implant materials and design. In Italy, dental implants are also very common.

According to Mr. Federico Annoni from Megagen Italia, the implant market is constantly growing in Italy due to the rapidly aging population and because many people neglect their oral health. This contributes to the loss of natural teeth. Thus, the use of implants is necessary.

Oral home care is very important for the health of dental implants, he adds. Proper oral hygiene combined with regular use of Lumoral could be decisive in preventing periodontitis and peri-implantitis.

Megagen will participate at the Expodental Meeting with two stands – one exclusively dedicated to Megagen products (A3 - Stand 30) and another devoted solely to Lumoral (C3 - Stand 187) where specialists from both Megagen Italia and Koite Health will be present.

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Facts: Global Dental Implants Market

• 50 million implants have been inserted globally so far, while 10 million new implants are being inserted in patients' mouths each year. Maintaining the health of implants is crucial.

• Peri-implantitis is a serious gum disease that impacts the health of implants and can lead to loss of them, if left untreated. Despite impressive success rates, one implant is still lost every four minutes, which translates into 140,000 cases per year.

• Around 50% of implant patients will develop peri-implant mucositis over time. Approximately one-third of all patients will develop clinically manifested peri-implantitis.

(Source: Dentognostics)